If you havn't yet heard about Silverlight,
"Microsoft® Silverlight™ is a cross-browser, cross-platform plug-in for delivering the next generation of .NET based media experiences and rich interactive applications for the Web. Silverlight offers a flexible programming model that supports AJAX, VB, C#, Python, and Ruby, and integrates with existing Web applications. Silverlight supports fast, cost-effective delivery of high-quality video to all major browsers running on the Mac OS or Windows."
Here is more info - http://silverlight.net/
You can watch more details and tutorials here
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